PRODUCT DETAILS

About Brutiz 400mg/2mg Capsule

IBUPROFEN+TIZANIDINE belongs to the class of medications called ‘analgesics’ used in treating acute muscle spasms associated with low back pain. Low back pain, also called lumbago, is a condition that affects the lower portion of the spine. It often occurs due to injury, strain, or sprain in the muscles, bones, or ligaments present in the lower back. In most cases, the only symptom of this condition is a pain in the lower back.

IBUPROFEN+TIZANIDINE contains Ibuprofen and Tizanidine. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing prostaglandins' production (chemical substances that cause pain and inflammation) at the affected site (muscle) and reduce pain. Tizanidine is a short-acting muscle relaxant. It works by reducing the activity of the nerves in the brain that control muscles. This effect helps to reduce muscle spasms, thereby improving pain and muscle movements.

Uses of Brutiz 400mg/2mg Capsule

Low back pain

Medicinal Benefits of Brutiz 400mg/2mg Capsule

IBUPROFEN+TIZANIDINE is used to treat acute pain associated with muscle spasms that usually occur due to muscle strains, sprains or injuries in the lower back. It contains ibuprofen and tizanidine. Ibuprofen can reduce pain, swelling and inflammation in the muscles, whereas tizanidine can reduce muscle spasms and pain.  It provides fast relief from pain, within a few hours after taking this medicine. It reduces muscle stiffness and enables the easy movement of the muscle. It is well tolerated when taken at recommended doses. For the best results, rest and physical therapy are also essential along with this medicine as it will help to strengthen your back.

Directions for Use

IBUPROFEN+TIZANIDINE is available in the form of tablets. Tablets should be swallowed as a whole with a glass of water. Do not crush, chew, or break the tablet. The dose and duration of IBUPROFEN+TIZANIDINE are determined by the doctor based on your health condition. Take this medicine with food to avoid side-effects associated with the stomach and intestine.

Side Effects of Brutiz 400mg/2mg Capsule

• Drowsiness
• Tiredness
• Dizziness
• Low blood pressure
• Dry mouth
• Nausea
• Stomach upset
• Heartburn
• Abdominal pain
• Indigestion
• Decrease or increase in heart rate

Similar Drugs

For informational purposes only. Consult a doctor before taking any medicines.

In-Depth Precautions and Warning

Drug Warnings

Before taking IBUPROFEN+TIZANIDINE, inform your doctor if you have any liver, kidney, or heart problems, diabetes, high cholesterol, high blood pressure, respiratory problems, systemic lupus erythematosus (a skin disease), porphyria (an inherited blood disorder), blood clotting problems, and ulcerative colitis (inflammation of the colon). IBUPROFEN+TIZANIDINE increases the risk of ulcers, bleeding, and perforation in the stomach or intestine when taken in high doses. It may also increase the risk of heart attack or stroke when used in high doses. IBUPROFEN+TIZANIDINE may increase the risk of kidney damage, especially in patients who have liver, kidney, or heart problems, and who are taking water pills. IBUPROFEN+TIZANIDINE may affect the function of platelets (form clots) and prolong bleeding time, so it should be used with caution in patients with blood clotting problems. IBUPROFEN+TIZANIDINE is an anti-inflammatory and can mask the symptoms of an infection, so consult your doctor if you feel unwell while using this medicine.

Drug Interactions

Drug-Drug Interaction:

Drug-Drug Interactions: IBUPROFEN+TIZANIDINE may interact with other NSAIDs, blood thinners (warfarin, heparin, clopidogrel, and ticlopidine), medicines used to treat abnormal heart rhythms (amiodarone, mexiletine, and propafenone), a medicine used to treat stomach ulcer (cimetidine), antibiotics (enoxacin, pefloxacin, and norfloxacin), painkiller (rofecoxib), oral contraceptives, medicines used to treat high blood pressure including water pills, beta-blockers (atenolol and propranolol), a medicine used to treat heart disease (digoxin), sleeping pill (temazepam), a medicine used to treat cancer (methotrexate), a medicine used to treat fits (phenytoin), antidepressants (lithium, paroxetine, and sertraline), a medicine used to treat high cholesterol (cholestyramine), anti-HIV drugs (zidovudine and ritonavir), a medicine used to treat gout (probenecid), muscle relaxant (baclofen), and antifungal medicines (voriconazole and fluconazole).

Drug-Disease Interaction:

IBUPROFEN+TIZANIDINE should not be used in patients with bleeding or ulcers in the stomach or intestine, severe liver, kidney, or heart problems, severe dehydration (due to vomiting or diarrhoea), active bleeding (including in the brain), and conditions that cause the abnormal formation of red blood cells.

Safety Advice

ALCOHOL

Consumption of alcohol increases the risk of side-effects, such as drowsiness, liver damage, and bleeding in the stomach.

PREGNANCY

IBUPROFEN+TIZANIDINE is usually not recommended during pregnancy, especially if you are more than six months pregnant as it may cause harmful effects to the unborn baby.

BREAST FEEDING

IBUPROFEN+TIZANIDINE may pass into breastmilk and cause unwanted effects in the nursing baby. So, it is not prescribed in breastfeeding mothers. However, if prescribed, the doctor may advise you to stop breastfeeding while using this medicine

DRIVING

IBUPROFEN+TIZANIDINE may cause dizziness or drowsiness, so do not drive or operate heavy machinery if you are not fully alert

LIVER

IBUPROFEN+TIZANIDINE should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.

KIDNEY

IBUPROFEN+TIZANIDINE should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor